Boehmenan
(Synonyms:赤麻木脂素;赤麻木脂素标准品,对照品)
目录号 : KE3901
CAS No. : 57296-22-7
纯度 : ≥95%
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells.
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| 生物活性 |
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell lines, boehmenan-mediated anti-tumor property is mediated by modulation of mitochondria and EGFR signaling pathway in A549 NSCLC cells.
|
| 分子式 |
C40H40O12
|
| 分子量 |
712.74
|
| CAS号 |
57296-22-7
|
| 中文名称 |
赤麻木脂素
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|