p53 Activator 15 is an orally active p53 Y220C activator. p53 Activator 15 enhances the DNA binding of p53 Y220C (SC50 = 0.58 nM) and significantly inhibits NUGC-3 cell proliferation. p53 Activator 15 effectively inhibits tumor growth in NUGC-3 xenograft mouse and rat models. p53 Activator 15 can be used to study gastric cancer.
分子式
C27H27D3F4N6O4S
分子量
613.64
CAS号
3069395-29-2
运输条件
Room temperature in continental US; may vary elsewhere.