Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
| Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| KP1387 | 5A2-SC8 | 1857341-90-2 |
|
|
| KG12990 | CIN-16645 | 1799316-64-5 | >90% |
|
| KM31963 | DSPE-PEG-Cy5, MW 2000 |
|
||
| KP18922 |
DSPE-PEG-SH, MW 1000
DSPE-PEG-SH (MW 1000) 是一种两亲性聚 PEG,可在水中形成脂质双层。该两性聚合物可在水溶液中形成脂质双分子层,可用于包埋活性分子,用于药物递送系统,如mRNA疫苗。 |
≥95% |
|
|
| KP18935 |
DSPE-PEG-SH, MW 10000
DSPE-PEG-SH,MW 10000 是一种马来酰亚胺反应性 PEG 脂质。该两亲性聚合物可在水中形成脂质双层,可用于制备脂质体,作为药物纳米载体,以输送 mRNA、DNA 或 siRNA。试剂级,仅供研究使用。 |
≥95% |
|
|
| KP18933 | DSPE-PEG-SH, MW 2000 | 98% |
|
|
| KP18923 |
DSPE-PEG-SH, MW 5000
DSPE-PEG-SH, MW 5000 是聚 PEG 连接的 DSPE 分子。 脂质尾部允许在水中形成脂质双层,并可用于溶解疏水性药物,而亲水性核心可封装治疗剂,例如核酸(mRNA/DNA)、蛋白质或肽。 试剂级,仅供研究使用。 |
≥95% |
|
|
| KG13070 | NT1-O14B | 2739805-64-0 | >95% |
|
| KP18033 |
TCL053
TCL053 是一种可电离的脂质,用于高效地将活性成分 (特别是核酸) 导入细胞。TCL053 能够与二棕榈酰磷脂酰胆碱 (DPPC)、聚乙二醇二肉豆蔻酰基甘油 (PEG-DMG) 和胆固醇,一起形成脂质纳米粒 (LNP),能够将 Cas9 mRNA 和 sgRNA 传递到骨骼肌中。 |
2361162-70-9 | 99% |
|
| KG12936 | YSK05 | 1318793-78-0 | >90% |
|
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