Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
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KP1387 | 5A2-SC8 | 1857341-90-2 |
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KG12990 | CIN-16645 | 1799316-64-5 | >90% |
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KG13070 | NT1-O14B | 2739805-64-0 | >95% |
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KP18033 |
TCL053
TCL053 是一种可电离的脂质,用于高效地将活性成分 (特别是核酸) 导入细胞。TCL053 能够与二棕榈酰磷脂酰胆碱 (DPPC)、聚乙二醇二肉豆蔻酰基甘油 (PEG-DMG) 和胆固醇,一起形成脂质纳米粒 (LNP),能够将 Cas9 mRNA 和 sgRNA 传递到骨骼肌中。 |
2361162-70-9 | 99% |
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KG12936 | YSK05 | 1318793-78-0 | >90% |
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