| 生物活性 |
YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization.
|
|---|---|
| 分子式 |
C19H18N2O2
|
| 分子量 |
306.36
|
| CAS号 |
1373764-75-0
|
| 中文名称 |
YH-306
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
|
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