all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; ECs = 77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 µM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid , which is a metabolite of vitamin A.
all-trans-5,6-epoxy Retinoic acid is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s=77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 μM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid, which is a metabolite of vitamin A.
IC50&Target
Human Endogenous Metabolite
分子式
C20H28O3
分子量
316.4
CAS号
13100-69-1
中文名称
六氯化萘
运输条件
Room temperature in continental US; may vary elsewhere.