Salicylcurcumin - CAS:1236545-54-2

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Salicylcurcumin

目录号 : KCM10770 CAS No. : 1236545-54-2 纯度 : ≥95%

Data Sheet 产品使用指南

Curcuminoids are natural and synthetic analogs of curcumin , a natural polyphenol with modulating effects in inflammation, cancer, and immunity. Salicylcurcumin is a synthetic curcuminoid which, like bisdemethoxycurcumin , lacks methoxy groups on both phenols. Furthermore, the hydroxyl groups on each phenol are positioned ortho, as in salicylates, rather than in the para position typical of curcuminoids. Salicylcurcumin has antioxidant and anticarcinogenic properties. Also, it increases the activity of quinone reductase in mouse hepatoma cells in a dose-dependent fashion, doubling activity at 0.3 μM salicylcurcumin.

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock
10mg		In-stock

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生物活性

Salicylcurcumin is a synthetic curcumin analogue with antioxidant activity. Salicylcurcumin may affect lipid peroxidation in fish, favoring increased survival, disease resistance, and ultimately growth rate.

体外研究

Salicylcurcumin (0.1-10 mM) can inhibit the formation of lipid peroxidation products and the content of thiobarbituric acid reactive substances (TBARS) in vitro [1].

体内研究

Salicylcurcumin can enhance the activity of antioxidant enzymes (such as superoxide dismutase) and inhibit catalase (CAT) and glutathione peroxidase (GPx) [1].

分子式

C₁₉H₁₆O₄

分子量

308.3

CAS号

1236545-54-2

中文名称

(1E,4Z,6E)-5-Hydroxy-1,7-bis(2-hydroxyphenyl)-1,4,6-heptatrien-3- one

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥95%

Data Sheet

产品使用指南

[1]. Manju M, et al. Curcumin analogue inhibits lipid peroxidation in a freshwater teleost, Anabas testudineus (Bloch)--an in vitro and in vivo study. Fish Physiol Biochem. 2009 Aug;35(3):413-20.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系客服）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

配置后的溶液总体积：

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

Other Forms of Rapamycin:

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The molarity calculator equation

The dilution calculator equation

动物实验计算换算器