(2S)-OMPT - CAS:1217471-69-6

您当前的位置：

(2S)-OMPT (Synonyms:(2S)-OMPT triethylamine；(2S)-OMPT (三乙胺))

目录号 : KCM10680 CAS No. : 1217471-69-6 纯度 : ≥98%

Data Sheet 产品使用指南

Lysophosphatidic acid (LPA) is a potent lipid mediator that elicits its effect through four distinct receptors - LPA/EDG-2, LPA/EDG-4, LPA/EDG-7 and LPA/GPR23. OMPT is a selective agonist of the lysophosphatidic acid 3 (LPA) receptor. It exhibits EC values of 68 nM and >6.8 µM for calcium mobilization in LPA and LPA-expressing Sf9 cells, respectively. The (2S)-OMPT enantiomer is 5- to 20-fold more active than (2R)-OMPT in calcium release assays in both LPA-transfected Sf9 and rat hepatoma Rh7777 cells.

规格	价格	是否有货	数量
500μg		In-stock
1mg		In-stock
5mg		In-stock
10mg		In-stock

加入购物车大包装询价

Other Forms of Rapamycin:

Anti-IL11 Antibody (X203) In-stock
BI-765423 In-stock
InVivo Plus Anti-Mouse osteopontin/SPP1 Antibody (103D6) In-stock
Romiplostim In-stock
Anti-Mouse PD-1 Antibody (29F.1A12) In-stock

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。

生物活性

(2S)-OMPT (triethylamine), Lysophosphatidic acid analogue, is a LPA3 G-protein-coupled receptor agonist. (2S)-OMPT (triethylamine) selectively activates LPA3 G-protein-coupled receptor to trigger downstream cellular signaling events. (2S)-OMPT (triethylamine) induces calcium, IL-6 release in cancer cells and activates MAPK and Akt signaling pathways. (2S)-OMPT (triethylamine) can be used for the research of ovarian cancer.

IC₅₀&Target

IL-6

体外研究

(2S) - OMPT (0.001-10000 nM) (triethylamine) can induce the release of calcium ions from human ovarian cancer cell line OVCAR3, with an EC50 of 9.0 nM.

(2S) - OMPT (0.01-1 μM) (triethylamine) can activate the phosphorylation of Akt and MAPK in human ovarian cancer OVCAR3 cells.

(2S) - OMPT (0.01-10 μM) (triethylamine) can induce the release of IL-6 in human ovarian cancer cell line OVCAR3.

分子式

C₂₂H₄₃O₆PS^.₂(C₂H₅)₃N

分子量

669

CAS号

1217471-69-6

中文名称

(2S)-OMPT (三乙胺)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥98%

Data Sheet

产品使用指南

暂无相关参考文献

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

浓度

体积

分子量*

重置计算

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度

体积

浓度

体积

重置计算

动物实验计算换算器

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系客服为您提供正确的澄清溶液配方）

% DMSO

% Tween 80

% ddH₂O

% DMSO

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系客服）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

配置后的溶液总体积：

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

Other Forms of Rapamycin:

KKL 顾客使用本产品发表的 0 篇科研文献

The molarity calculator equation

The dilution calculator equation

动物实验计算换算器