D73-IN-14 is a potent, selective and orally active CD73 inhibitor with an IC50 value of 0.17 nM. CD73-IN-14 increases the number of tumor-infiltrating CD8+ cells and shows anti-tumor activity. CD73-IN-14 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
分子式
C26H26ClN7O9
分子量
615.98
CAS号
2407356-67-4
中文名称
CD73-IN-14
运输条件
Room temperature in continental US; may vary elsewhere.