| 生物活性 |
Tebanicline (ABT-594, Ebanicline) acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. Tebanicline is an effective synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analog of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, Tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound.
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 分子式 |
C9H11ClN2O
|
||||||||||||
| 分子量 |
198.65
|
||||||||||||
| CAS号 |
198283-73-7
|
||||||||||||
| 中文名称 |
替巴克兰
|
||||||||||||
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
||||||||||||
| 储存方式 |
|
纯度： ≥95%
关注我们
获得KKL MED 最新资讯
咨询热线：
400-881-9290
Data Sheet