CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Ki) of 330 nM.
体外研究
CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2.
CMPD1 induced mitotic arrest and apoptosis in U87 cells.
CMPD1 inhibits tubulin polymerisation in glioblastoma cells.
分子式
C22H20NO2F
分子量
349.40
CAS号
41179-33-3
运输条件
Room temperature in continental US; may vary elsewhere.