| 生物活性 |
Apomine, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 分子式 |
C28H52O7P2
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| 分子量 |
562.66
|
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| CAS号 |
126411-13-0
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
|
纯度： ≥95%
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