GN44028 is a hypoxia inducible factor (HIF)-1 inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization.
IC50&Target
IC50: 14 nM (HIF-1).
分子量
305.33
CAS号
1421448-26-1
运输条件
Room temperature in continental US; may vary elsewhere.