SCH-37370
(Synonyms:N- Acetyl去loratadine;N-乙酰地氯雷他定;N-乙酰基地氯雷他定;聚季铵盐-1;乙酰地氯雷他定)
目录号 : KE7872
CAS No. : 117796-52-8
纯度 : ≥95%
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
Other Forms of Rapamycin:
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生物活性 |
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
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分子式 |
C21H21ClN2O
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分子量 |
352.86
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CAS号 |
117796-52-8
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中文名称 |
乙酰地氯雷他定
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Store at -20˚C
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