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(3Z)-5-(pyridin-3-yl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one (Synonyms:5-pyridin-3-yl-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one)
目录号 : KE7854 CAS No. : 454234-24-3 纯度 : ≥95%
Data Sheet 产品使用指南
(3Z)-5-(pyridin-3-yl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.
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生物活性
(3Z)-5-(pyridin-3-yl)-3-[(1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.
分子式
C18H13N3O
分子量
287.322
CAS号
454234-24-3
中文名称
5-pyridin-3-yl-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2-one
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Store at -20˚C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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