| 生物活性 |
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.
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| 分子式 |
C41H48O11
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| 分子量 |
716.81
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| CAS号 |
88497-88-5
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| 中文名称 |
木脂素
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO: 10 mg/mL (13.95 mM; Need ultrasonic and warming) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
纯度： ≥95%
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