653-47 hydrochloride, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 hydrochloride is also a very weak CREB inhibitor with IC50 of 26.3 μM.
体外研究
653-47 (5-10 μM) synergistically inhibits CREB-mediated gene transcription with 666-15.
分子式
C20H20Cl2N2O3
分子量
407.29
CAS号
1224567-46-7
运输条件
Room temperature in continental US; may vary elsewhere.