Butyrolactone 3 is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 shows weak inhibitory on CBP (IC50=0.5 mM)
IC50&Target
GCN5
100 μM (IC50)
分子式
C9H12O4
分子量
184.19
CAS号
778649-18-6
运输条件
Room temperature in continental US; may vary elsewhere.