CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).
IC50 value: 2.3 nM (FAK); 120 nM (ALK cellular IC50 in 75% human plasma)
Target: Dual FAK/ALK
Preparation of fused bicyclic 2,4-diaminopyrimidine derivatives as a dual ALK and FAK inhibitor
By Jacobs, Martin J.; Ott, Gregory R.
From PCT Int. Appl. (2013), WO 2013134353 A1 20130912.
分子式
C30H38N7O3Cl
分子量
580.12
CAS号
1391712-60-9
运输条件
Room temperature in continental US; may vary elsewhere.