1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1.
IC50&Target
P450 1B1
体外研究
1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%.
分子式
C12H8
分子量
152.19
CAS号
15727-65-8
中文名称
1-乙炔萘;1-乙炔基萘
运输条件
Room temperature in continental US; may vary elsewhere.