| 生物活性 |
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity.
|
|---|---|
| 分子式 |
C59H68F3N13O6S
|
| 分子量 |
1144.31
|
| CAS号 |
2769753-53-7
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
Store at -20˚C
|
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