ABM-14 是一种靶向雄激素受体 (AR) 的配体,用于设计 PROTAC。ABM-14 通过 linker 与 VHL 配体结合形成雄激素受体降解剂 ARCC-4 。
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ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 to degrade AR.
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