NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction.
IC50&Target
DCN1
体外研究
NAcM-OPT (Compound 67) is orally bioavailable, well tolerated in mice, and currently used to study the effects of acute pharmacologic inhibition of the DCN1-UBE2M interaction on the NEDD8/CUL pathway.
分子式
C23H29Cl2N3O
分子量
434.40
CAS号
2089293-61-6
运输条件
Room temperature in continental US; may vary elsewhere.