2-Iodomelatonin 是褪黑激素受体 1 (MT1) 的强效激动剂，Ki 为 28 pM，对 MT1的选择性是 MT2 的 5 倍以上。2-Iodomelatonin 可用于鉴定，表征和定位脑和周围组织的褪黑激素结合位点。
| 生物活性 |
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues. |
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| 体外研究 |
2-iodomelatonin (0-7.5 μM; 18 hours) shares the protective properties of melatonin, it inhibits cell death of mutant htt ST14A and inhibits the increase in Rip2 expression in stressed mutant htt ST14A cells. Cell Viability Assay
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| 分子式 |
C13H15N2O2I
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| 分子量 |
358.17
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| CAS号 |
93515-00-5
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| 中文名称 |
2-碘褪黑激素
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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纯度： 98%
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