Ro 3-1314 is an inhibitor of both COX and lipoxygenase. Ro 3-1314 inhibits ram seminal vesicle COX with a K of 0.6 µM. It is a more effective inhibitor of COX-1 than of 15-LO, inhibiting 95% and 68%, respectively, of these enzymatic activities when used at a concentration of 48 µM.
9,12-Octadecadiynoic Acid is a plant lipoxygenase inhibitor. 9,12-Octadecadiynoic Acid is a linoleic acid metabolism inhibitor. 9,12-Octadecadiynoic Acid stimulates the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substance of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments.
分子式
C18H28O2
分子量
276.41
CAS号
2012-14-8
运输条件
Room temperature in continental US; may vary elsewhere.