Eicosapentaenoyl Serotonin
目录号 : KCM12356 CAS No. : 199875-71-3 纯度 : ≥98%
Eicosapentaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin . Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain. The effects of replacing the arachidonoyl portion with eicosapentaenoic acid have not been studied. However, replacement of arachidonate with saturated 11- or 12-carbon fatty acids produces compounds that potently inhibit capsaicin-induced TRPV1 channel activation (IC = 0.76 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamide (IC > 50 μM).
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5mg
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25mg
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分子式
C30H40N2O2
分子量
460.7
CAS号
199875-71-3
中文名称
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]icosa-5,8,11,14,17-pentaenamide
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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