1-Palmitoyl Lysophosphatidic Acid (sodium salt) - CAS:17618-08-5

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1-Palmitoyl Lysophosphatidic Acid (sodium salt) (Synonyms:1-P-GPA sodium salt)

目录号 : KCM12002 CAS No. : 17618-08-5 纯度 : ≥98%

Data Sheet 产品使用指南

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of Pseudomonas aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca and Mg.

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock
10mg		In-stock
25mg		In-stock

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Other Forms of Rapamycin:

4A3-SC8 In-stock
DSPE-PEG-Amine, MW 3400 ammonium In-stock
DSPE-PEG2000-triGalNAc ammonium In-stock
DSPE-PEG-Amine, MW 2000 ammonium In-stock
DSPE-PEG Carboxylic acid (sodium), MW 2000 In-stock

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生物活性

1-Palmitoyl Lysophosphatidic Acid (sodium salt) is a type of phospholipid and a precursor of lipid membranes. 1-Palmitoyl Lysophosphatidic Acid (sodium salt) can be incorporated into POPC liposomes, resulting in significant changes in membrane curvature. 1-Palmitoyl Lysophosphatidic Acid (sodium salt) can induce platelet aggregation, but its activity is 30 times lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate.

体外研究

1-Palmitoyl Lysophosphatidic Acid (sodium salt) can induce platelet suspension aggregation, with a half maximal effective concentration of 290 nM.

分子式

C₁₉H₃₈O₇P^.Na

分子量

432.46

CAS号

17618-08-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

H2O : 50 mg/mL (115.62 mM; Need ultrasonic)

Methanol : 2.5 mg/mL (5.78 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.3124 mL	11.5618 mL	23.1235 mL
5 mM	0.4625 mL	2.3124 mL	4.6247 mL
10 mM	0.2312 mL	1.1562 mL	2.3124 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥98%

Data Sheet

产品使用指南

暂无相关参考文献

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

浓度

体积

分子量*

重置计算

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度

体积

浓度

体积

重置计算

动物实验计算换算器

第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）

给药剂量

mg/kg

动物平均体重

每只动物给药体积

动物数量

只

第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系客服为您提供正确的澄清溶液配方）

% DMSO

% Tween 80

% ddH₂O

% DMSO

计算重置

计算结果:

工作液浓度： mg/ml；

DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系客服）；

体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH₂O，混匀澄清。

配置后的溶液总体积：

注意：1. 首先保证母液是澄清的；
2. 一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。

Other Forms of Rapamycin:

KKL 顾客使用本产品发表的 0 篇科研文献

The molarity calculator equation

The dilution calculator equation

动物实验计算换算器