Chlorotoluron is a phenylurea herbicide that has been used to control growth of broad-leaved weeds in winter wheat, rye, barley, and triticale crops. It is genotoxic, inducing formation of chromosome aberrations and sister chromatid exchange (SCE) in a concentration-dependent manner in CHEL liver epithelial cells. Chlorotoluron (625-5,000 mg/kg) induces testicular anaplasia as well as looseness and incrassation to the basement membrane that destroys the blood-testis barrier, increases superoxide dismutase (SOD) activity, and degrades mitochondria in mice. It reduces food intake and body weight and induces hemolytic anemia, hemosiderosis of the spleen, and brown atrophy in dogs when administered at a dose of 9,200 ppm.
Chlorotoluron is a urea herbicide. Chlorotoluron serves as a degradation substrate that undergoes dissipation in soil and produces demethylated chlorotoluron metabolites via N-dealkylation. Chlorotoluron is used for pre-emergence and post-emergence weed control in cereals and various other crops.
体外研究
Chlorodoron is a urea herbicide that can be used for pre - and post emergence weed control in grains and various other crops.
分子式
C10H13ClN2O
分子量
212.68
CAS号
15545-48-9
中文名称
绿麦隆
运输条件
Room temperature in continental US; may vary elsewhere.