3’-sulfo Galactosylsphingosine (ammonium salt) (Synonyms:Psychosine 3′-O-sulfate ammonium; Psychosine 3′-sulfate ammonium; Lyso-sulfatide (bovine) ammonium)
目录号 : KCM10816 CAS No. : 1246681-32-2 纯度 : ≥98%
3’-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 µM. It also inhibits PKC and cytochrome c oxidase activity when used at concentrations of 150 and 50-100 µM, respectively. 3’-sulfo Galactosylsphingosine accumulates in patients with metachromatic leukodystrophy, a lysosomal storage disorder characterized by arylsulfatase A (ASA) deficiency leading to progressive demyelination and neuromotor deficits. In mice lacking ASA, levels of 3’-sulfo galactosylsphingosine increase after one month of age followed by demyelination and neuromotor deficits. 3’-sulfo Galactosylsphingosine has been used as a standard for the quantification of 3’-sulfo galactosylsphingosine by LC-MS.
规格 价格 是否有货 数量
1mg
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生物活性

3’-sulfo Galactosylsphingosine (ammonium salt) a derivative of the glycosphingolipid sulfatide, acts as an extracellular signal regulating the migration of a neural precursor cell line (B35 neuroblastoma cells) by rapidly promoting process retraction and cell rounding.

分子式
C24H46NO10S.NH4
分子量
558.73
CAS号
1246681-32-2
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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