(R)-nitro-Blebbistatin
目录号 : KCM10686 CAS No. : 1217619-62-9 纯度 : ≥98%
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (–)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereochemistry as the inactive (+)-blebbistatin enantiomer.
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1mg
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5mg
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10mg
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Other Forms of Rapamycin:

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生物活性

(R)-nitro-Blebbistatin is an analog of (-)-Blebbistatin. (-)-Blebbistatin is a selective non-muscle myosin II inhibitor.

分子式
C17H13N3O4
分子量
323.3
CAS号
1217619-62-9
中文名称
R-(-)-7-Desmethyl-8-nitro blebbistatin
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
暂无相关参考文献
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动物实验计算换算器
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
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计算结果:

工作液浓度 mg/ml;

DMSO母液配制方法 mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,

体内配方配制方法μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL ddH2O,混匀澄清。

配置后的溶液总体积

1. 首先保证母液是澄清的;
           2. 一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。