(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (R)-(-)-JQ1 Enantiomer has no effect.
IC50&Target
BET bromodomain
体外研究
(R)-(-)-JQ1 Enantiomer shows no significant interaction with any bromodomain. Besides, (R)-(-)-JQ1 Enantiomer is comparatively inactive in nuclear protein in testis (NUT) midline carcinoma (NMC).
分子式
C23H25ClN4O2S
分子量
456.99
CAS号
1268524-71-5
运输条件
Room temperature in continental US; may vary elsewhere.