Tpl2 Kinase Inhibitor 1 (Compound 1) is a potent and selective Tpl2 (COT kinase, MAP3K8) inhibitor, plays an important role in the regulation of the inflammatory response and the progression of some cancers.
IC50&Target
MAP3K8
体外研究
Cancer Osaka thyroid (COT) kinase (Tpl2) is an important regulator of pro-inflammatory cytokines in macrophages.
分子式
C21H14N6FCl
分子量
404.83
CAS号
871307-18-5
运输条件
Room temperature in continental US; may vary elsewhere.