Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.
体内研究
Danicamtiv selectively enhances cardiac actomyosin activity, the molecular force‐generating unit of the sarcomere, prolonging contraction while preserving actin–myosin detachment, allowing relaxation, and without impacting Ca homeostasis.
分子式
C16H20F3N5O4S
分子量
435.42
CAS号
1970972-74-7
运输条件
Room temperature in continental US; may vary elsewhere.