EN40 是一种有效的选择性乙醛脱氢酶 3A1 (ALDH3A1) 抑制剂，一种共价配体，IC50 值为 2 uM。
| 生物活性 |
EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM |
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| 体外研究 |
EN40 (10-1000 μM; 48 hours) shows inhibitory effecton ALDH3A1 activity and impairs A549 cell survival. Cell Viability Assay
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| 体内研究 |
EN40 (intraperitoneal injection; 50mg/kg; from 14 days; once per day) exerts strong anti-tumorigenic effects in established A549 tumor xenografts, shows good tolerability with no body weight loss in mice.
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| 分子式 |
C13H15NO2
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| 分子量 |
217.26
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| CAS号 |
2094547-67-6
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
4°C, stored under nitrogen *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
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| 溶解性数据 |
In Vitro:
DMSO : 5 mg/mL (23.01 mM; Need ultrasonic) Ethanol : 2 mg/mL (9.21 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
纯度： 95%
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