IM-12
目录号 : KF1146
CAS No. : 129669-05-1
纯度 : 98%
IM-12 (129669-05-1) is a potent and selective inhibitor of glycogen synthase kinase 3ß (GSK-3ß) IC50=53 nM which induces neuronal differentiation. Activates the Wnt-ß-catenin signaling pathway and attenuates tissue plasminogen activator-induced hemorrhagic transformation after acute ischemic stroke in animal models. Promoted hair follicle growth in vitro and antagonized the inhibition of hair follicles by dihydrotestosterone. Down-regulates Sox9 expression in limbal epithelial stem/progenitor cells leading to increased differentiation.
Other Forms of Rapamycin:
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| 分子式 |
C22H20FN3O2
|
| 分子量 |
377.41
|
| CAS号 |
129669-05-1
|
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