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p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1.

p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC₅₀ of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC₅₀ of 7.3 μM.
p32 Inhibitor M36 is selective for p32 overexpressing cells.
p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC₅₀ of 2.8 μM.

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