6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.
IC50&Target
Human Endogenous Metabolite
体外研究
6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions.
分子式
C9H11N5O3
分子量
237.22
CAS号
22150-76-1
中文名称
L-生物喋呤;L-生物蝶呤
运输条件
Room temperature in continental US; may vary elsewhere.