Pep2-8 binds to C-terminally truncated PCSK9.
Pep2-8 restored LDL uptake of PCSK9-treated HepG2 cells to about 90% of control activity at a concentration of 50 μM.
Cell Viability Assay
Cell Line: |
HepG2 cell. |
Concentration: |
15 μg/mL. |
Incubation Time: |
4 h. |
Result: |
Inhibited PCSK9 activity. |