Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity.
IC50&Target
ratACAT
24.6 μM (IC50)
体外研究
Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells.
分子式
C25H28O4
分子量
392.49
CAS号
59870-65-4
中文名称
光甘草醇
运输条件
Room temperature in continental US; may vary elsewhere.