Acivicin (Synonyms:阿西维辛; AT-125; U-42126)
目录号 : KM16001 CAS No. : 42228-92-2 纯度 : 98%

Acivicin (AT-125) 是一种由猪链霉菌产生的天然产物,是 γ-谷氨酰转肽酶 (GGT) 抑制剂。Acivicin 可以透过血脑屏障,并具有抗癌,抗寄生虫的特性。

规格 价格 是否有货 数量
1mg
In-stock
5mg 询价 In-stock
10mg 询价 In-stock

Other Forms of Rapamycin:

KKL Med 的所有产品和服务仅用于科学研究,不能被用于人体,兽医,我们也不向个人提供产品和服务。
生物活性

Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.

体外研究

Acivicin (AT-125; 0.1-50 μM; 5 days) has an IC50 of 0.7 μM in human HepG2 cells.

体内研究

Acivicin (AT-125; 5 mg/kg; IP; twice weekly) reduces urinary γ-GT by 70-78%.

Animal Model: Male pigmented Long-Evans rats weighed between 250 g and 300 g exposed to Toluene
Dosage: 5 mg/kg
Administration: IP; twice weekly (monday and wednesday)
Result: Reduced urinary γ-GT by 70-78%.
分子式
C5H7N2O3Cl
分子量
178.57
CAS号
42228-92-2
中文名称
阿西维辛;异恶唑醋酸
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

溶解性数据
In Vitro: 

H2O : 6.67 mg/mL (37.35 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.6000 mL 28.0002 mL 56.0004 mL
5 mM 1.1200 mL 5.6000 mL 11.2001 mL
10 mM 0.5600 mL 2.8000 mL 5.6000 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
在线客服
咨询热线
400-881-9290
关注微信公众号