Ribostamycin sulfate - CAS:53797-35-6

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Ribostamycin sulfate (Synonyms:硫酸核糖霉素; Vistamycin sulfate)

目录号 : KM15572 CAS No. : 53797-35-6 纯度 : ≥98%

Data Sheet 产品使用指南

Ribostamycin sulfate (Vistamycin sulfate) 是一种广谱抗菌剂, 在30S和50S核糖体亚基结合水平抑制细菌蛋白质合成, 还抑制蛋白二硫键异构酶 (PDI) 分子伴侣活性, 用于药代动力学和肾毒性研究。

规格	价格	是否有货
50mg		In-stock
100mg	询价	In-stock
200mg	询价	In-stock

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Other Forms of Rapamycin:

AMOZ In-stock
Nalidixic acid sodium salt In-stock
Amorolfine HCL In-stock
Ormetoprim In-stock
Cuprous iodide In-stock

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生物活性

Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies

体外研究

Ribostamycin is as an intermediate in the biosynthesis of neomycin.
Ribostamycin inhibited the chaperone activity of protein disulfide isomerase (PDI), but it did not inhibit the isomerase activity.
Ribostamycin is effective against both gram-positive and gram-negative cocci and bacilli including drug-resistant strains. Ribostamycin is especially effective against the gentamicin-resistant bacterium Klebsiella pneumoniae, which possesses aminoglycoside-modifying enzymes.

分子式

C₁₇H₃₆N₄O₁₄S

分子量

552.55

CAS号

53797-35-6

中文名称

硫酸核糖霉素；核糖霉素硫酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

H₂O : 130 mg/mL (235.27 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.8098 mL	9.0490 mL	18.0979 mL
5 mM	0.3620 mL	1.8098 mL	3.6196 mL
10 mM	0.1810 mL	0.9049 mL	1.8098 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

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