α-MSH (Synonyms:α-Melanocyte-Stimulating Hormone)
目录号 : KM14081 CAS No. : 581-05-5 纯度 : 98%

α-MSH (alpha-melanocyte-stimulating hormone) 作为内源性神经肽,是一种内源性 melanocortin receptor 4 (MC4R) 激动剂,具有抗炎、解热作用。α-MSH 是前阿皮黑素皮质激素 (POMC) 的翻译后衍生物。

规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock
10mg
In-stock
25mg
In-stock
50mg 询价 In-stock
100mg 询价 In-stock

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生物活性

α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC).

体外研究

α-MSH modulates CNS inflammation by acting directly on melanocortin receptors in glial cells. α-MSH modulates NFκB activation. α-MSH inhibits translocation of transcription factor κB to the nucleus.

体内研究

α-MSH (50 µg/0.2 ml saline; i.p.) given systemically effectively modulates inflammatory reactions.

Animal Model: IL-10–deficient mice
Dosage: 50 µg/0.2 ml saline
Administration: I.p.
Result: Given systemically effectively modulated inflammatory reactions.
分子式
C77H109N21O19S
分子量
1664.88
CAS号
581-05-5
中文名称
α-黑素细胞刺激激素 (MSH),酰胺
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 50 mg/mL (30.03 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6006 mL 3.0032 mL 6.0064 mL
5 mM 0.1201 mL 0.6006 mL 1.2013 mL
10 mM 0.0601 mL 0.3003 mL 0.6006 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

科研文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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