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Calyculin A (Synonyms:(--Calyculin A))
目录号 : KM12896 CAS No. : 101932-71-2
Data Sheet 产品使用指南

Calyculin A ((-)-Calyculin A) 是有效，可渗透细胞的蛋白磷酸酶 1 (PP1) 和蛋白磷酸酶 2A (PP2A) 抑制剂，其 IC50 值分别为 2 nM 和 0.5-1 nM。

规格 价格 是否有货 数量
10μg
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Other Forms of Rapamycin:

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生物活性

Calyculin A ((-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 2 nM and 0.5-1 nM, respectively.

体外研究

Calyculin A (1-10 nM; 24 hours) induces cytotoxicity in MG63 cells in a dose-dependent manner up to 10 nM in MG63 cells.

Cell Cytotoxicity Assay

Cell Line: Human osteosarcoma MG63 cells
Concentration: 0, 1, 2, 5, 10 nM
Incubation Time: 24 hours
Result: Treatment with 0.1 nM for 24 h had a minimal effect on MG63 cell survival. Cell rounding and shrinking were obvious in the cultures treated for 24 h with 5 nM. The level of the cell viability treated with 10 nM was 27% that of the control cultures.
分子式
C50H81N4O15P
分子量
1009.17
CAS号
101932-71-2
中文名称
花萼海绵诱癌素；花萼海绵体诱癌素A
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
科研文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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