Ammonium iron(III) citrate (Ammonium ferric citrate) 是一种非运铁蛋白结合的铁的生理形式，会引起的细胞内铁超负荷从而导致细胞铁死亡 (ferroptosis)。Ammonium iron(III) citrate 可以增强蛋白质的产生。
| 生物活性 |
Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis. Ammonium iron(III) citrate can enhance protein production. |
|---|---|
| 体外研究 |
Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter. |
| 分子式 |
C6H11FeNO7
|
| 分子量 |
265
|
| CAS号 |
1185-57-5
|
| 中文名称 |
柠檬酸铁 (III) 铵
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| 溶解性数据 |
In Vitro:
H2O : 33.33 mg/mL (Need ultrasonic) DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble) |
| 科研文献 |
纯度： ≥95%
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