| 生物活性 |
PROTACs TTK degrader-2 is a potent TTK (threonine tyrosine kinase) PROTACs degrader, with DC50 values of 3.1 and 12.4 nM in COLO-205 and HCT-116 cell, respectively. PROTACs TTK degrader-2 exhibits target degradation and anticancer efficacy in a xenograft mouse model of COLO-205 human colorectal cancer cells.
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| 分子式 |
C49H57N9O7
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| 分子量 |
884.03
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| CAS号 |
2953426-48-5
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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