PROTACs TTK degrader-2 is a potent TTK (threonine tyrosine kinase) PROTACs degrader, with DC50 values of 3.1 and 12.4 nM in COLO-205 and HCT-116 cell, respectively. PROTACs TTK degrader-2 exhibits target degradation and anticancer efficacy in a xenograft mouse model of COLO-205 human colorectal cancer cells.
分子式
C49H57N9O7
分子量
884.03
CAS号
2953426-48-5
运输条件
Room temperature in continental US; may vary elsewhere.