| 生物活性 |
Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti-HER3 (ERBB3) monoclonal antibody. Lumretuzumab effectively inhibits the activity of key oncogenic signaling pathways such as PI3K/AKT and MAPK. Lumretuzumab has been optimized through glycosyl engineering to enhance antibody-dependent cell-mediated cytotoxicity (ADCC). Lumretuzumab can be used to study HER3-positive, HER2-low-expressing solid tumors, especially breast cancer.
|
|---|---|
| 分子量 |
146.92 kDa
|
| CAS号 |
1448327-63-6
|
| 中文名称 |
鲁妥珠单抗
|
| 运输条件 |
Shipping with dry ice.
|
| 储存方式 |
Store at -20˚C
|
纯度： ≥99%
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