PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA.
分子式
C126H249NO52
分子量
2610.29
CAS号
1443687-74-8
中文名称
[3-[3-(2-甲氧基乙氧基)丙基氨基甲酰氧基]-2-十四烷酰氧基丙基]十四烷酸酯
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)