ATX-1905
目录号 : KM38801 CAS No. : 3035983-65-1
ATX-1905 是一种正电子发射断层扫描 (PET) 示踪剂,显示出良好的自脂酶 (ATX) 结合特异性,并实现了对纤维化肺中升高的 ATX 表达水平的半定量评估。ATX-1905 在Bleomycin 诱导的肺纤维化 (BPF) 模型中显示出显著的摄取。ATX-1905 有望用于特发性肺纤维化 (IPF) 的研究。
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生物活性
ATX-1905 is a positron emission tomography (PET) tracer that demonstrates good autotaxin (ATX) binding specificity and achieves semiquantification of lung ATX expression levels, which are elevated in fibrotic lungs. ATX-1905 exhibits elevated uptake in Bleomycin -induced pulmonary fibrosis (BPF) lungs. ATX-1905 is promising for research of idiopathic pulmonary fibrosis (IPF).
分子式
C32H33D4ClFN9Os
分子量
654.24
CAS号
3035983-65-1
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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