| 生物活性 |
Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group.
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| 分子式 |
C10H15N5O13P2S
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| 分子量 |
507.26
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| CAS号 |
482-67-7
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| 中文名称 |
3’-腺苷酸、5’-（磷酸二氢钠）、5’-酸酐和硫酸
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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