Rapirosiran sodium
(Synonyms:(ALN-HSD sodium))
目录号 : KM34781
CAS No. : 2755197-77-2
Rapirosiran sodium 是一种与 N-乙酰半乳糖胺结合的小干扰 RNA,它靶向肝脏中表达的羟基类固醇 17-β 脱氢酶 13(HSD17B13) 的 mRNA。HSD17B13 的功能缺失变异体与慢性肝病的风险降低有关。
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| 生物活性 |
Rapirosiran sodium is a N-acetylgalactosamine-conjugated small-interfering RNA targeting liver-expressed hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) mRNA. Loss-of-function variants in the HSD17B13 associated with reduced risk of chronic liver disease. Rapirosiran sodium can be used for the study of Non-alcoholic steatohepatitis.
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| 分子量 |
16307.22 (free acid)
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| CAS号 |
2755197-77-2
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
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-20°C |
1 month |
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