(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC50 of 144 nM.
IC50&Target
PARP-1
144 nM (IC50)
体外研究
(8R,9S)-Talazoparib shows an EC50 of 864 nM in cellular PARylation assay.
(8R,9S)-Talazoparib shows an EC50 of 1135 nM for Capan-1 cells (BRCA2 mutant).
分子式
C19H14N6OF2
分子量
380.35
CAS号
1207456-00-5
中文名称
他拉唑帕利 (8R,9S)
运输条件
Room temperature in continental US; may vary elsewhere.